PNPLA3 rs738409 underlies treatment response in nonalcoholic fatty liver disease
نویسندگان
چکیده
منابع مشابه
Nonalcoholic Fatty Liver Disease Treatment
Nonalcoholic fatty liver disease (NAFLD) is increasing in pediatric age group parallel to the growing prevalence of obesity and overweight all around the world. So changing in life style and interventions on obesogenic environment is cornerstone of NAFLD therapy in obese children. Some experts recommend that children and adolescents be encouraged to follow a low-fat, low-glycemic-index diet t...
متن کاملAssociation of rs738409 Polymorphism in the PNPLA3 Gene with Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease and has an estimated incidence of 20%–30% in the general population and 67%–75% in the obese population. Genetic predisposition can play an important role in development of this disease. Nonsynonymous coding SNP rs738409 C/G (I148Met) in the PNPLA3 gene has been found to be associated with the presence of...
متن کاملNonalcoholic fatty liver disease and the PNPLA3 gene.
Nonalcoholic fatty liver disease, a potentially fatal obesity-related condition, affects more than 70 million people in the United States. Nurses are well-positioned to impact this genetically influenced disease by is increasing awareness, providing patient education, and advocating for affected persons.
متن کاملnonalcoholic fatty liver disease treatment
nonalcoholic fatty liver disease (nafld) is increasing in pediatric age group parallel to the growing prevalence of obesity and overweight all around the world. so changing in life style and interventions on obesogenic environment is cornerstone of nafld therapy in obese children. some experts recommend that children and adolescents be encouraged to follow a low-fat, low-glycemic-index diet t...
متن کاملAntioxidant treatment in nonalcoholic fatty liver disease.
Vitamin E is one of the most important lipid-soluble antioxidants, and it prevents lipid peroxidation and scavenges free radicals. As oxidative stress takes a role in the pathogenesis of nonalcoholic steatohepatitis (NASH), vitamin E supplementation acts as a promising therapeutic strategy. In a phase 3, multicenter, randomized, placebo-controlled, double-blind clinical trial (PIVENS) by Sanyal...
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ژورنال
عنوان ژورنال: World Journal of Clinical Cases
سال: 2018
ISSN: 2307-8960
DOI: 10.12998/wjcc.v6.i8.167